HERBAL ANALYSIS: CHROMATOGRAPHY
In drug discovery researches
from natural sources, such as plants and animals, crude extracts of specimens
containing hundreds of compounds are often used for initial biological
screening. Once a hit extract is identified, we need to isolate/separate active
principles by using various chromatographic techniques such as HPLC, TLC, GC, etc.
Chromatographic separation
techniques are also used for the identification of herbal drug constituents
in a crude mixture: i.e.
STANDARDISATION of crude drug preparations and essential
oils.
The selection of a specific chromatographic technique to be used for
separation of mixtures requires knowledge and experience both on the chemistry
of the possible constituents in question as well as chromatographic techniques.
Applying crude samples through the wrong chromatographic method not only give
inadequate separations and inaccurate results but also could destroy expensive
columns and loss of precious samples. Please click
here
for more information on chromatographic
principles and theory! Further notes on modes of chromatography and their
applications are also available via this
link.
Our core chromatographic systems for herbal
medicines quality control and metabolic profiling are based on:
HPLC fingerprint
analysis
Gas Chromatography (GC)
study
GC-MS analysis of essential oils
LC-MS analysis and metabolic profiling
For
any REQUEST ON HERBAL-RELATED chromatography or collaboration studies please
contact the site owner
or
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