Patchouli essential oil has been
extensively used for centuries both in the perfumery industry and for
medicinal purposes. The chemistry of this oil is by far the most interesting as
it contains only one group of chemical classes called sesquiterpenes. Since most
of the constituents are incredibly similar in their molecular mass and
structure, their identification is based on the use of GC-MS analysis with due
reference to mass spectral databasis. Patchoulol or patchouli alcohol (see below) is the major constituent which
is often used as a quality marker as it is responsible for most of the
characteristic scents of patchouli essential oil.
Below is the GC-MS
analysis trace of one commercially available pactchoui essential oil.
The above content analysis together with
physical measurements such as optical activity, refractive index,
density/specific gravity, etc are routine assays that we perform for assuring
the quality of patchouli essential oil.
Dr Habtemariam BSc, MSc,
PhD........FRSM, FRSC. .... With a
Principal Lecturer post at Greenwich, Dr Habtemariam
has been a leader of courses and
researches on bioassay & natural products-based drug
addition to our fully equipped tissue culture
facilities, we have access to various
state-of-the-art equipment including ICP-MS, LC-MS,
MALDI-TOF-MS, FABS-MS, FTIR, Laser-Raman,
scanning and transmission electron
microscopes, flow cytometer, NMR (270, 300
and 500MHz), automated DNA sequencers, various HPLC
systems, capillary electrophersis ................